Pre-existing hypertension complicating pregnancy, childbirth and the puerperium

hypertension: Persistently high systemic arterial blood pressure. Based on multiple readings (blood pressure determination), hypertension is currently defined as when systolic pressure is consistently greater than 140 mm Hg or when diastolic pressure is consistently 90 mm Hg or more.

Endpoint definition

FinnGen phenotype data
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Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 O10
Hospital discharge: ICD-9 6420
Cause of death: ICD-10 O10
Cause of death: ICD-9 6420

Check pre-conditions None

Include endpoints None

Check conditions None

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Apply sex-specific rule

Sex only females
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Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF3
Parent code in ICD-10 O10-O16
Name in latin Hypertensio prae-existens graviditatem, partum et/sive puerperium complicans

Summary Statistics

Key figures

All Female Male
Number of individuals 1367 1367 -
Unadjusted prevalence (%) 0.53 0.93 -
Mean age at first event (years) 32.81 32.81 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.35 [1.16, 4.74] 1.7e-2 15
15 years - - - -
5 years - - - -
1 year - - - -

Correlations

Index endpoint: O15_EXIST_HYPERT_COMPLIC – Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
GWS hits: 1

Survival analyses between endpoints

Plot

before Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
after Pre-existing hypertension complicating pregnancy, childbirth and the puerperium

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Drugs most likely to be purchased after Pre-existing hypertension complicating pregnancy, childbirth and the puerperium