Gestational [pregnancy-induced] hypertension

DOID EFO MESH SNOMED PheWeb

preeclampsia: Preeclampsia is a hypertensive disorder of pregnancy that is characterized by new-onset hypertension with proteinuria presenting after 20 weeks of gestation, and depending on mild or severe forms may initially present with severe headache, visual disturbances, and hyperreflexia.

Endpoint definition

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FinnGen phenotype data

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 O13

Hospital discharge: ICD-9 6423

Hospital discharge: ICD-8 63701

Cause of death: ICD-10 O13

Cause of death: ICD-9 6423

Cause of death: ICD-8 63701

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule

Sex only females

O15_GESTAT_HYPERT

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF5

Parent code in ICD-10 O10-O16

Name in latin Hypertensio gestationalis sine proteinuria significanti

Similar endpoints

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List of similar endpoints to Gestational [pregnancy-induced] hypertension based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	5240	5240	-
Unadjusted prevalence (%)	2.02	3.57	-
Mean age at first event (years)	29.99	29.99	-

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.07 [0.76, 1.52]	6.9e-1	109
15 years	0.01	0.99 [0.67, 1.47]	9.8e-1	50
5 years	-	-	-	-
1 year	-	-	-	-

Correlations

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Index endpoint: O15_GESTAT_HYPERT – Gestational [pregnancy-induced] hypertension
GWS hits: 3

Survival analyses between endpoints

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Plot

before Gestational [pregnancy-induced] hypertension
after Gestational [pregnancy-induced] hypertension

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Table

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Drugs most likely to be purchased after Gestational [pregnancy-induced] hypertension

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