Cleft lip and cleft palate

cleft lip: ['Congenital defect in the upper lip where the maxillary prominence fails to merge with the merged medial nasal prominences. It is thought to be caused by faulty migration of the mesoderm in the head region.']

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 Q35-Q37
Cause of death: ICD-10 Q35-Q37

Check pre-conditions None

Check conditions None

Apply sex-specific rule None

diagram downward connector Q17_CLEFT_LIP_CLEFT_PALATE

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF4
Parent code in ICD-10 Q
Name in latin Cheiloschisis et palatoschisis

Summary Statistics

Key figures

All Female Male
Number of individuals 204 122 82
Unadjusted prevalence (%) 0.08 0.08 0.07
Mean age at first event (years) 23.27 23.62 22.75

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Correlations

Index endpoint: Q17_CLEFT_LIP_CLEFT_PALATE – Cleft lip and cleft palate
GWS hits: 1

Survival analyses between endpoints

Plot

before Cleft lip and cleft palate
after Cleft lip and cleft palate

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Cleft lip and cleft palate