Endpoint definition
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FinnGen phenotype data
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COPD_EARLYANDLATER
Extra metadata
First used in FinnGen datafreeze
DF2
COPD, early/later onset
chronic obstructive pulmonary disease: A chronic and progressive lung disorder characterized by the loss of elasticity of the bronchial tree and the air sacs, destruction of the air sacs wall, thickening of the bronchial wall, and mucous accumulation in the bronchial tree. The pathologic changes result in the disruption of the air flow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough, and chest tightness. The two main types of chronic obstructive pulmonary disease are chronic obstructive bronchitis and emphysema.
COPD_EARLYANDLATER
Similar endpoints
↥List of similar endpoints to
COPD, early/later onset
based on the number of shared cases.
Broader endpoints:
- Other chronic obstructive pulmonary disease
- COPD
- Other chronic obstructive pulmonary disease
- Chronic lower respiratory diseases
- Excluding asthma or asthma-COPD overlap
Narrower endpoints:
Summary Statistics
↥Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 9140 | 2771 | 6369 |
| Unadjusted prevalence (%) | 3.51 | 1.89 | 5.63 |
| Mean age at first event (years) | 63.96 | 60.38 | 65.52 |
Mortality
| Follow-up | Absolute risk | HR [95% CI] | p | N |
|---|---|---|---|---|
| 1998–2019 | - | - | - | - |
| 15 years | - | - | - | - |
| 5 years | - | - | - | - |
| 1 year | - | - | - | - |
Correlations
↥
Index endpoint: COPD_EARLYANDLATER – COPD, early/later onset
GWS hits:
Survival analyses between endpoints
↥Plot
before COPD, early/later onset
after COPD, early/later onset
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Table
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