Hypereosinophilic syndrome: The hypereosinophilic syndrome (HES) is a disease characterized by a persistently elevated eosinophil count (≥ 1500 eosinophils/mm³) in the blood for at least six months without any recognizable cause, with involvement of either the heart, nervous system, or bone marrow. HES is a diagnosis of exclusion, after clonal eosinophilia (such as leukemia) and reactive eosinophilia (in response to infection, autoimmune disease, atopy, hypoadrenalism, tropical eosinophilia, or cancer) have been ruled out.
Filter registries Inpat., Oupat., Death
Check pre-conditions None
Include endpoints None
Check conditions None
Apply sex-specific rule None
ESOSINOPHIL_DISEASE
Extra metadata
List of similar endpoints to
Eosinophilic disease (BM)
based on the number of shared cases.
Broader endpoints:
Narrower endpoints:
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 222 | 117 | 105 |
| Unadjusted prevalence (%) | 0.09 | 0.08 | 0.09 |
| Mean age at first event (years) | 53.45 | 50.82 | 56.37 |
| Follow-up | Absolute risk | HR [95% CI] | p | N |
|---|---|---|---|---|
| 1998–2019 | 0.02 | 1.35 [0.44, 4.19] | 6.0e-1 | 22 |
| 15 years | 0.01 | 1.60 [0.53, 4.85] | 4.0e-1 | 18 |
| 5 years | - | - | - | - |
| 1 year | - | - | - | - |
Index endpoint: ESOSINOPHIL_DISEASE – Eosinophilic disease (BM)
GWS hits: 0
before Eosinophilic disease (BM)
after Eosinophilic disease (BM)
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