Hypothyroidism, levothyroxin purchases

hypothyroidism: Abnormally low levels of thyroid hormone.

Endpoint definition

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FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries KELA purch., KELA reimb.

Medicine purchases: ATC H03AA01
Medicine purchases: ATC: other data required >3 instances required

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector HYPOTHY_LEVOTHY

Extra metadata

First used in FinnGen datafreeze DF3

Similar endpoints

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List of similar endpoints to Hypothyroidism, levothyroxin purchases based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 32576 26120 6456
Unadjusted prevalence (%) 12.53 17.77 5.71
Mean age at first event (years) 52.32 50.94 57.89

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.86 [1.65, 2.09] 6.5e-25 2083
15 years 0.01 2.01 [1.80, 2.24] 2.9e-36 1658
5 years 0.00 2.55 [2.26, 2.88] 4.5e-51 577
1 year 0.00 1.69 [1.30, 2.20] 1.0e-4 70

Correlations

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Index endpoint: HYPOTHY_LEVOTHY – Hypothyroidism, levothyroxin purchases
GWS hits: 37

Survival analyses between endpoints

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Plot

before Hypothyroidism, levothyroxin purchases
after Hypothyroidism, levothyroxin purchases

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Drugs most likely to be purchased after Hypothyroidism, levothyroxin purchases

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