Crohn's disease patients in KELA-register (KELA code 209, or 208 with ICD K50)

Crohn's disease: A gastrointestinal disorder characterized by chronic inflammation involving all layers of the intestinal wall, noncaseating granulomas affecting the intestinal wall and regional lymph nodes, and transmural fibrosis. Crohn disease most commonly involves the terminal ileum; the colon is the second most common site of involvement.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries KELA purch., KELA reimb.

KELA reimbursements: KELA codes 208
KELA reimbursements: ICD-10 K50

Check pre-conditions None

diagram bullet diagram downward connector

Include endpoints

Check conditions None

Apply sex-specific rule None

diagram downward connector K11_KELACROHN

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF3

Similar endpoints

List of similar endpoints to Crohn's disease patients in KELA-register (KELA code 209, or 208 with ICD K50) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 1177 679 498
Unadjusted prevalence (%) 0.45 0.46 0.44
Mean age at first event (years) 41.41 40.68 42.40

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.75 [0.34, 1.66] 4.8e-1 22
15 years 0.01 0.87 [0.39, 1.92] 7.2e-1 17
5 years - - - -
1 year - - - -

Correlations

Index endpoint: K11_KELACROHN – Crohn's disease patients in KELA-register (KELA code 209, or 208 with ICD K50)
GWS hits: 4

Survival analyses between endpoints

Plot

before Crohn's disease patients in KELA-register (KELA code 209, or 208 with ICD K50)
after Crohn's disease patients in KELA-register (KELA code 209, or 208 with ICD K50)

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Crohn's disease patients in KELA-register (KELA code 209, or 208 with ICD K50)