Unspecified diabetes with ophthalmic complications

diabetic retinopathy: A chronic, pathological complication associated with diabetes mellitus, where retinal damages are incurred due to microaneurysms in the vasculature of the retina, progressively leading to abnormal blood vessel growth, and swelling and leaking of fluid from blood vessels, resulting in vision loss or blindness.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 E12.3+, E13.3+, E14.3+
Hospital discharge: ICD-9 2504C|2503X
Cause of death: ICD-10 E12.3+, E13.3+, E14.3+
Cause of death: ICD-9 2504C|2503X

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector E4_DMNASOPTH

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF3

Summary Statistics

Key figures

All Female Male
Number of individuals 47 16 31
Unadjusted prevalence (%) 0.02 0.01 0.03
Mean age at first event (years) 51.17 50.00 51.77

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Correlations

Index endpoint: E4_DMNASOPTH – Unspecified diabetes with ophthalmic complications
GWS hits:

Survival analyses between endpoints

Plot

before Unspecified diabetes with ophthalmic complications
after Unspecified diabetes with ophthalmic complications

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Drugs most likely to be purchased after Unspecified diabetes with ophthalmic complications