Hypothyroidism, levothyroxin purchases

hypothyroidism: Abnormally low levels of thyroid hormone.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries KELA purch., KELA reimb.

Medicine purchases: ATC H03AA01
Medicine purchases: ATC: other data required >3 instances required

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector HYPOTHY_LEVOTHY

Extra metadata

First used in FinnGen datafreeze DF3

Similar endpoints

List of similar endpoints to Hypothyroidism, levothyroxin purchases based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 32576 26120 6456
Unadjusted prevalence (%) 12.53 17.77 5.71
Mean age at first event (years) 52.32 50.94 57.89


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.86 [1.65, 2.09] 6.5e-25 2083
15 years 0.01 2.01 [1.80, 2.24] 2.9e-36 1658
5 years 0.00 2.55 [2.26, 2.88] 4.5e-51 577
1 year 0.00 1.69 [1.30, 2.20] 1.0e-4 70


Index endpoint: HYPOTHY_LEVOTHY – Hypothyroidism, levothyroxin purchases
GWS hits: 37

Survival analyses between endpoints


before Hypothyroidism, levothyroxin purchases
after Hypothyroidism, levothyroxin purchases

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Drugs most likely to be purchased after Hypothyroidism, levothyroxin purchases