Other/unspecified rheumatoid arthritis

rheumatoid arthritis: A chronic, systemic autoimmune disorder characterized by inflammation in the synovial membranes and articular surfaces. It manifests primarily as a symmetric, erosive polyarthritis that spares the axial skeleton and is typically associated with the presence in the serum of rheumatoid factor.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 M06.8, M06.9
Hospital discharge: ICD-9 7148
Hospital discharge: ICD-8 7123[8-9]
Cause of death: ICD-10 M06.8, M06.9
Cause of death: ICD-9 7148
Cause of death: ICD-8 7123[8-9]

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector RHEUMA_NOS

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 2462 1745 717
Unadjusted prevalence (%) 0.95 1.19 0.63
Mean age at first event (years) 48.35 47.33 50.83

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.09 [1.50, 2.92] 1.4e-5 422
15 years 0.02 2.45 [1.81, 3.32] 7.7e-9 333
5 years 0.00 4.66 [3.60, 6.02] 6.1e-32 154
1 year 0.00 7.24 [5.06, 10.37] 2.4e-27 46

Correlations

Index endpoint: RHEUMA_NOS – Other/unspecified rheumatoid arthritis
GWS hits: 4

Survival analyses between endpoints

Plot

before Other/unspecified rheumatoid arthritis
after Other/unspecified rheumatoid arthritis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other/unspecified rheumatoid arthritis