Other/unspecified rheumatoid arthritis

rheumatoid arthritis: A chronic, systemic autoimmune disorder characterized by inflammation in the synovial membranes and articular surfaces. It manifests primarily as a symmetric, erosive polyarthritis that spares the axial skeleton and is typically associated with the presence in the serum of rheumatoid factor.

Endpoint definition

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FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 M06.8, M06.9
Hospital discharge: ICD-9 7148
Hospital discharge: ICD-8 7123[8-9]
Cause of death: ICD-10 M06.8, M06.9
Cause of death: ICD-9 7148
Cause of death: ICD-8 7123[8-9]

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector RHEUMA_NOS

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 2462 1745 717
Unadjusted prevalence (%) 0.95 1.19 0.63
Mean age at first event (years) 48.35 47.33 50.83

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.09 [1.50, 2.92] 1.4e-5 422
15 years 0.02 2.45 [1.81, 3.32] 7.7e-9 333
5 years 0.00 4.66 [3.60, 6.02] 6.1e-32 154
1 year 0.00 7.24 [5.06, 10.37] 2.4e-27 46

Correlations

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Index endpoint: RHEUMA_NOS – Other/unspecified rheumatoid arthritis
GWS hits: 4

Survival analyses between endpoints

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Plot

before Other/unspecified rheumatoid arthritis
after Other/unspecified rheumatoid arthritis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other/unspecified rheumatoid arthritis

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