Type 2 diabetes, wide definition

type II diabetes mellitus: A type of diabetes mellitus that is characterized by insulin resistance or desensitization and increased blood glucose levels. This is a chronic disease that can develop gradually over the life of a patient and can be linked to both environmental factors and heredity.

Endpoint definition

FinnGen phenotype data
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Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 E11
Hospital discharge: ICD-9 250.A
Cause of death: ICD-10 E11
Cause of death: ICD-9 250.A

Check pre-conditions None

Include endpoints None

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Check conditions

not PANCREATITIS

Apply sex-specific rule None

diagram downward connector T2D_WIDE

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 E10-E14
Name in latin Diabetes (mellitus) [obesus/non obesus] adultorum

Summary Statistics

Key figures

All Female Male
Number of individuals 22058 9262 12796
Unadjusted prevalence (%) 8.48 6.30 11.32
Mean age at first event (years) 61.37 60.90 61.70

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 4.73 [4.17, 5.37] <1e-100 5323
15 years - - - -
5 years - - - -
1 year - - - -

Correlations

Index endpoint: T2D_WIDE – Type 2 diabetes, wide definition
GWS hits: 47

Survival analyses between endpoints

Plot

before Type 2 diabetes, wide definition
after Type 2 diabetes, wide definition

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Drugs most likely to be purchased after Type 2 diabetes, wide definition