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Type 2 diabetes, strict (exclude DM1)

DOIDEFOMESHSNOMED PheWeb

type II diabetes mellitus: A type of diabetes mellitus that is characterized by insulin resistance or desensitization and increased blood glucose levels. This is a chronic disease that can develop gradually over the life of a patient and can be linked to both environmental factors and heredity.

Endpoint definition

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FinnGen phenotype data
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Filter registries KELA purch., KELA reimb.

Medicine purchases: ATC A10B
Medicine purchases: ATC: other data required >3 instances required

Check pre-conditions None

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Include endpoints

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Check conditions

not E4_DM1

Apply sex-specific rule None

diagram downward connector E4_DM2_STRICT

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 36993 16828 20165
Unadjusted prevalence (%) 14.23 11.45 17.83
Mean age at first event (years) 60.05 59.26 60.71

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.65 [2.38, 2.95] 2.1e-70 5679
15 years 0.02 2.97 [2.72, 3.24] <1e-100 4843
5 years 0.00 4.09 [3.75, 4.46] <1e-100 1901
1 year 0.00 5.56 [4.78, 6.47] <1e-100 483

Correlations

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Index endpoint: E4_DM2_STRICT – Type 2 diabetes, strict (exclude DM1)
GWS hits: 107

Survival analyses between endpoints

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Plot

before Type 2 diabetes, strict (exclude DM1)
after Type 2 diabetes, strict (exclude DM1)

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Type 2 diabetes, strict (exclude DM1)

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