Other (seronegative) rheumatoid arthritis, wide

rheumatoid arthritis: A chronic, systemic autoimmune disorder characterized by inflammation in the synovial membranes and articular surfaces. It manifests primarily as a symmetric, erosive polyarthritis that spares the axial skeleton and is typically associated with the presence in the serum of rheumatoid factor.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 M06
Hospital discharge: ICD-9 7140B|7148|7142
Cause of death: ICD-10 M06
Cause of death: ICD-9 7140B|7148|7142

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector RHEUMA_OTHER_WIDE

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 M05-M14
Name in latin Alia arthritis rheumatoides

Summary Statistics

Key figures

All Female Male
Number of individuals 3831 2688 1143
Unadjusted prevalence (%) 1.47 1.83 1.01
Mean age at first event (years) 54.16 52.85 57.25

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.16 [1.26, 3.68] 4.9e-3 442
15 years 0.02 2.80 [1.87, 4.18] 4.9e-7 375
5 years 0.01 4.96 [3.72, 6.62] 1.0e-27 177
1 year 0.00 8.11 [5.69, 11.55] 4.4e-31 57

Correlations

Index endpoint: RHEUMA_OTHER_WIDE – Other (seronegative) rheumatoid arthritis, wide
GWS hits: 4

Survival analyses between endpoints

Plot

before Other (seronegative) rheumatoid arthritis, wide
after Other (seronegative) rheumatoid arthritis, wide

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other (seronegative) rheumatoid arthritis, wide