Other/unspecified seropositiverheumatoid arthritis

rheumatoid arthritis: A chronic, systemic autoimmune disorder characterized by inflammation in the synovial membranes and articular surfaces. It manifests primarily as a symmetric, erosive polyarthritis that spares the axial skeleton and is typically associated with the presence in the serum of rheumatoid factor.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 M05.8, M05.9
Hospital discharge: ICD-9 7140A
Cause of death: ICD-10 M05.8, M05.9
Cause of death: ICD-9 7140A

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector RHEUMA_SEROPOS_OTH

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 5793 4083 1710
Unadjusted prevalence (%) 2.23 2.78 1.51
Mean age at first event (years) 53.86 52.57 56.93

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.45 [1.95, 3.08] 1.4e-14 688
15 years 0.02 2.71 [2.22, 3.29] 2.9e-23 536
5 years 0.00 3.40 [2.79, 4.13] 2.0e-34 181
1 year 0.00 2.80 [1.87, 4.20] 6.0e-7 28

Correlations

Index endpoint: RHEUMA_SEROPOS_OTH – Other/unspecified seropositiverheumatoid arthritis
GWS hits: 23

Survival analyses between endpoints

Plot

before Other/unspecified seropositiverheumatoid arthritis
after Other/unspecified seropositiverheumatoid arthritis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other/unspecified seropositiverheumatoid arthritis