Other/unspecified seropositiverheumatoid arthritis

rheumatoid arthritis: A chronic, systemic autoimmune disorder characterized by inflammation in the synovial membranes and articular surfaces. It manifests primarily as a symmetric, erosive polyarthritis that spares the axial skeleton and is typically associated with the presence in the serum of rheumatoid factor.

Endpoint definition

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FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 M05.8, M05.9
Hospital discharge: ICD-9 7140A
Cause of death: ICD-10 M05.8, M05.9
Cause of death: ICD-9 7140A

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector RHEUMA_SEROPOS_OTH

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 5793 4083 1710
Unadjusted prevalence (%) 2.23 2.78 1.51
Mean age at first event (years) 53.86 52.57 56.93

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.45 [1.95, 3.08] 1.4e-14 688
15 years 0.02 2.71 [2.22, 3.29] 2.9e-23 536
5 years 0.00 3.40 [2.79, 4.13] 2.0e-34 181
1 year 0.00 2.80 [1.87, 4.20] 6.0e-7 28

Correlations

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Index endpoint: RHEUMA_SEROPOS_OTH – Other/unspecified seropositiverheumatoid arthritis
GWS hits: 23

Survival analyses between endpoints

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Plot

before Other/unspecified seropositiverheumatoid arthritis
after Other/unspecified seropositiverheumatoid arthritis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other/unspecified seropositiverheumatoid arthritis

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