Inflammatory bowel disease

inflammatory bowel disease: A spectrum of small and large bowel inflammatory diseases of unknown etiology. It includes Crohn's disease, ulcerative colitis, and colitis of indeterminate type.

Endpoint definition

FinnGen phenotype data

Filter registries None

Check pre-conditions None

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Include endpoints

Check conditions None

Apply sex-specific rule None

diagram downward connector K11_IBD

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF2

Similar endpoints

List of similar endpoints to Inflammatory bowel disease based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 7205 3865 3340
Unadjusted prevalence (%) 2.77 2.63 2.95
Mean age at first event (years) 41.65 40.10 43.43

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.62 [1.26, 2.08] 1.6e-4 470
15 years 0.01 1.95 [1.57, 2.42] 1.2e-9 356
5 years 0.00 3.61 [2.89, 4.51] 7.8e-30 158
1 year 0.00 5.38 [3.80, 7.60] 1.7e-21 45

Correlations

Index endpoint: K11_IBD – Inflammatory bowel disease
GWS hits: 19

Survival analyses between endpoints

Plot

before Inflammatory bowel disease
after Inflammatory bowel disease

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Drugs most likely to be purchased after Inflammatory bowel disease