Finngen Rheumatological endpoints

rheumatic disease: Inflammatory and degenerative diseases of connective tissue structures, such as arthritis.

Endpoint definition

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 56602 33122 23480
Unadjusted prevalence (%) 21.77 22.54 20.76
Mean age at first event (years) 55.42 54.46 56.77

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.50 [1.36, 1.66] 1.6e-15 5783
15 years 0.01 1.71 [1.56, 1.87] 3.5e-32 4584
5 years 0.00 2.59 [2.37, 2.83] 8.8e-99 1739
1 year 0.00 3.41 [2.94, 3.96] 2.0e-58 440

Correlations

Index endpoint: RHEUMA_ENDPOINTS – Finngen Rheumatological endpoints
GWS hits: 13

Survival analyses between endpoints

Plot

before Finngen Rheumatological endpoints
after Finngen Rheumatological endpoints

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Drugs most likely to be purchased after Finngen Rheumatological endpoints